ncRNA name | hsa-miR-638 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell lines Y79 and RBL-13 |
Methods | CCK-8, flow cytometry, Western blot, qRT-PCR |
Expression pattern | down-regulated |
Functional description | GRh2 functioned in cell proliferation, apoptosis and autophagy in Y79 and RBL-13 cells through miR-638-mediated up-regulation of p53 and inactivation of the PI3K/AKT/mTOR pathway. |
PubMed ID | 30853612 |
Year | 2019 |
Title | Ginsenoside Rh2 inhibits proliferation but promotes apoptosis and autophagy by down-regulating microRNA-638 in human retinoblastoma cells. |
Drug-related ncRNA | YES (Ginsenoside Rh2) |
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