logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-638
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell lines Y79 and RBL-13
Methods CCK-8, flow cytometry, Western blot, qRT-PCR
Expression pattern down-regulated
Functional description GRh2 functioned in cell proliferation, apoptosis and autophagy in Y79 and RBL-13 cells through miR-638-mediated up-regulation of p53 and inactivation of the PI3K/AKT/mTOR pathway.
PubMed ID 30853612
Year 2019
Title Ginsenoside Rh2 inhibits proliferation but promotes apoptosis and autophagy by down-regulating microRNA-638 in human retinoblastoma cells.
Drug-related ncRNA YES (Ginsenoside Rh2)

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.